Question 2 on Massachussett's ballot last night was a policy proposal that would make the possession of a small amount of marijuana a civil offense: Offenders would have their marijuana confiscated, receive a $100 ticket, and be sent on their way, without the threat of jail and a lifelong criminal record. Question 2 will save taxpayers millions every year and bring Massachusetts’ marijuana law in line with common sense.
This initiative passed by a wide majority - approximately 2 to 1, making Massachussetts the first start to enact decriminalization via a ballot initiative.
Wednesday, November 5, 2008
Medical Marijuana legalized in Michigan
Last night the voters of Michigan passed a ballot to approve medical marijuana. Voters approved it by a large majority of approximately 63% yes to 37% no (as of the most current return data).
The bill legalizes the use of medical marijuana by patients with “debilitating medical conditions” when approved by a physician. Michigan will become the 13th state to legalize medical marijuana use
Here is the full text of Michigan's Proposition 08-01
The bill legalizes the use of medical marijuana by patients with “debilitating medical conditions” when approved by a physician. Michigan will become the 13th state to legalize medical marijuana use
Here is the full text of Michigan's Proposition 08-01
Marijuana May Fight Bacteria
According to a recent article in the New York times, researchers in Italy and Britain have found that the main active ingredient in marijuana — tetrahydrocannabinol (THC) and related compounds show promise as antibacterial agents, particularly against microbial strains that are already resistant to several classes of drugs.
Research in the 1950's tested various marijuana preparations to see how they responded to skin and other infections so it has been known for decades that cannabis sativa possesses antibacterial properties. Most people are unaware of this research, however.
Back then, researchers had little understanding about the chemical makeup of marijuana. The current research has helped increase scientific understanding of this topic. Giovanni Appendino and colleagues, of the University of the Eastern Piedmont, looked at the antibacterial activity of the five most common cannabinoids. All were effective against several common multiresistant bacterial strains, although, perhaps understandably, the researchers suggested that the nonpsychotropic cannabinoids might prove more promising for eventual use.
The researchers say they do not know how the cannabinoids work or whether they would be effective, as systemic antibiotics would require much more research and trials. But the compounds may prove useful sooner as a topical agent against methicillin-resistant Staphylococcus aureus, or MRSA, to prevent the microbes from colonizing on the skin.
The study was led by Giovanni Appendino, of the University of the Eastern Piedmont, and published in The Journal of Natural Products.
Research in the 1950's tested various marijuana preparations to see how they responded to skin and other infections so it has been known for decades that cannabis sativa possesses antibacterial properties. Most people are unaware of this research, however.
Back then, researchers had little understanding about the chemical makeup of marijuana. The current research has helped increase scientific understanding of this topic. Giovanni Appendino and colleagues, of the University of the Eastern Piedmont, looked at the antibacterial activity of the five most common cannabinoids. All were effective against several common multiresistant bacterial strains, although, perhaps understandably, the researchers suggested that the nonpsychotropic cannabinoids might prove more promising for eventual use.
The researchers say they do not know how the cannabinoids work or whether they would be effective, as systemic antibiotics would require much more research and trials. But the compounds may prove useful sooner as a topical agent against methicillin-resistant Staphylococcus aureus, or MRSA, to prevent the microbes from colonizing on the skin.
The study was led by Giovanni Appendino, of the University of the Eastern Piedmont, and published in The Journal of Natural Products.
Friday, October 24, 2008
A Molecular Link between the Active Component of Marijuana and Alzheimer's Disease Pathology
The journal of Molecular Pharmaceutics recently published an article about the molecular link between THC and Alzheimer's disease pathology. The abstract is below and a link to the full article is below the article.
http://pubs.acs.org/cgi-bin/abstract.cgi/mpohbp/2006/3/i06/abs/mp060066m.html
A Molecular Link between the Active Component of Marijuana and Alzheimer's Disease Pathology
and
Departments of Chemistry, Immunology, and Molecular Biology, Molecular and Integrated Neurosciences Department, The Skaggs Institute for Chemical Biology, and Worm Institute for Research and Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
Received June 11, 2006
Abstract:
Alzheimer's disease is the leading cause of dementia among the elderly, and with the ever-increasing size of this population, cases of Alzheimer's disease are expected to triple over the next 50 years. Consequently, the development of treatments that slow or halt the disease progression have become imperative to both improve the quality of life for patients and reduce the health care costs attributable to Alzheimer's disease. Here, we demonstrate that the active component of marijuana, 
9-tetrahydrocannabinol (THC), competitively inhibits the enzyme acetylcholinesterase (AChE) as well as prevents AChE-induced amyloid 
-peptide (A) aggregation, the key pathological marker of Alzheimer's disease. Computational modeling of the THC-AChE interaction revealed that THC binds in the peripheral anionic site of AChE, the critical region involved in amyloidgenesis. Compared to currently approved drugs prescribed for the treatment of Alzheimer's disease, THC is a considerably superior inhibitor of A aggregation, and this study provides a previously unrecognized molecular mechanism through which cannabinoid molecules may directly impact the progression of this debilitating disease.
Keywords: Cannabinoids; Alzheimer's disease; acetylcholinesterase
Web Release Date: August 9,
http://pubs.acs.org/cgi-bin/abstract.cgi/mpohbp/2006/3/i06/abs/mp060066m.html
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